Advances in the Investigation of Protein Adsorption

Advances in the Investigation of Protein Adsorption

Description

Multi-component lipid bilayers determine the basic structure of biological membranes. Their properties and interactions with different ions and molecules are essential for the well controlled interplay, material exchange and signaling between cellular compartments performing different functions. Adsorption of proteins and lateral organization of multi-component lipid bilayers are approached in this work from two perspectives. On one side, using conventional experimental techniques such as atomic force microscopy, ellipsometry and fluorescence microscopy, new insights are brought about the domain formation and the reversibility of binding of specific proteins. On the other side, based on less conventional sensing properties of plasmonic particles, a new, nanosized, and addressable sensing platform is established for the detection of lipid membrane-mediated interactions. This is the first experimental approach that combines successfully the lipid membranes with the concept of single particle LSPR sensing.


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Details

Author(s)
Cristina Luminita Baciu
Format
Paperback | 176 pages
Dimensions
152 x 229 x 10mm | 268g
Publication date
16 May 2010
Publisher
VDM Verlag
Publication City/Country
Saarbrucken, Germany
Language
English
Illustrations note
Illustrations, black and white
ISBN10
3639252160
ISBN13
9783639252163